Isolation and Characterization of Dryland Microfungi From Northern Insana as Potential Sources of Antibacterial Agents
Article Sidebar
Main Article Content
Abstract
Microfungi are one of the most extensively studied groups of microorganisms due to their remarkable ability to produce a diverse range of unique bioactive compounds. This study aimed to explore and characterize microfungi isolated from the drylands of North Insana as potential sources of sustainable antibacterial agents. The research methods included the isolation of microfungi, morphological identification, and evaluation of antibacterial activity using the disc diffusion method. Based on morphological characterization, microfungi isolated from the North Insana dry soil showed similarities to three genera, namely Mucor, Penicillium/Aspergillus, and Aspergillus. Antibacterial assays revealed that all three isolates exhibited varying degrees of activity, ranging from moderate to strong, against Staphylococcus aureus. Isolate 1 produced an inhibition zone of 7.6 ± 0.20 mm (moderate activity), isolate 2 produced 10.17 ± 0.06 mm (strong activity), and isolate 3 produced 10.77 ± 0.06 mm (strong activity). According to the Tukey test (p < 0.05), isolate 3 showed no significant difference from the standard antibiotic chloramphenicol (11.23 ± 0.15 mm), indicating a comparable antibacterial effectiveness. These results suggest that dryland-endemic microfungi possess adaptive biosynthetic capacities, enabling them to produce antibacterial secondary metabolites in response to extreme environmental stress. This potential reinforces the role of dryland microfungi as promising new sources of natural antibacterial compounds for sustainable biotechnological and health applications
Downloads
Article Details
This work is licensed under a Creative Commons Attribution 4.0 International License.
Copyright and Licensing
For all articles published in Fullerene Journal of Chemistry, Authors retain some copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution 4.0 International (CC BY 4.0) that allows others to share the work with an acknowledgment of the work's authorship and initial publication in this journal. Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgment of its initial publication in this journal. Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work. In addition, the article may be reused and quoted provided that the original published version is cited. These conditions allow for maximum use and exposure of the work while ensuring the authors receive proper credit.
Authors are free to:
- Share - copy and redistribute the material in any medium or format
- Adapt - remix, transform, and build upon the material for any purpose, even commercially.
Under the following terms:
- Attribution - You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.
- No additional restrictions - You may not apply legal terms or technological measures that legally restrict others from doing anything the license permits.
Notices: You do not have to comply with the license for elements of the material in the public domain or where your use is permitted by an applicable exception or limitation. No warranties are given. The license may not give you all of the permissions necessary for your intended use. For example, other rights such as publicity, privacy, or moral rights may limit how you use the material.